JRF vacancy in Drug discovery for Msc Biosciences

Central Drug Research Institute, Lucknow, U.P., invites applications for the following post.

Vacancy:
One Junior Research Fellow, to work with Amit Misra et al in the Pharmaceutics Division.

Research Area:
Modulation of innate immune responses of macrophages infected with Mycobacterium tuberculosis.

Minimum qualifications:
Master’s degree in the First class, in any of the Biological Sciences, with the course content having included Biochemistry and Immunology.
The candidate should also have obtained a First class in the Bachelor’s degree and in the School leaving examinations.
Only those candidates who have their own funding for fellowship (CSIR / UGC / DBT/ ICMR –JRF) need apply.

Project Description:
M. tuberculosis induces ‘alternate activation’ of macrophages. We wish to explore drugs and drug delivery strategies that rescue the infected macrophage from this phenotype and induce ‘classical’, bactericidal activation. The Fellow will be expected to undertake studies on the activation status of macrophages, by analysis of transcription profiles; protein expression and bioactivity profiles; and key events in cell biology such as phagosome-lysosome fusion and apoptosis.

Deadline:
The last date for receipt of CV is May 1 2008.
The process shall conclude by May 15, 2008

Selection Process:
Interested candidates may send a 1-page CV and a 200-word write-up on
“The Three Most Interesting Molecules of Macrophage Innate Immunity, and Why they Interest Me” by e-mail to amit.cdri@gmail.com .

There will be a short-listing of about 10-15 people, send them 2 of our recent papers in the area to read, and fix a date for an interview in consultation with them.

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